Multipe Sequence Alignments:
Probing of the Twilight Zone




You are given the two sequences HMGB_CHITE and HMGL_TRYBR (they are in SwissProt).

Assuming you know nothing about HMGL_TRYBR, construct a model of homology between these two proteins and conlude about some of the functions of HMGL_TRYBR.

This model should indicate which residues are homlogous between the two sequences.

How can you convince yourself this model is correct?

Questions should be sent to C.Notredame