Multipe Sequence Alignments:
Finding remote homologues
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  1. Fetch the sequence.

  2. Make a Blast against SwissProt to try to find homologues.

  3. Compare the remote homologues you may find using dottlet or dotter.

  4. Make a multiple alignment of the homologous segments you found.

  5. Make a psi-blast using any of the segments.

  6. make a multiple alignment to convince yourself of the similarity with the DNA ligase.

Questions should be sent to C.Notredame