Getting the best out of T-Coffee

  • M-Coffee

    The following dataset embeds two known structures that have been aligned using a struture alignment package (ref_aln.aln). Using this reference alignment, try to produce with M-Coffee an alignment as accurate as possible. Try to determine whether M-Coffee is more accurate than every indivdual method and if the combination is more than its parts.

    You can evaluate the accuracy of any M-Coffee alignment by comparing it with the structural reference using the following command:
    t_coffee -other_pg aln_compare -al1 ref_aln.aln -al2 [your aln]

  • Questions should be sent to C.Notredame